PKC–NF-κB are involved in CCL2-induced Na(v)1.8 expression and channel function in dorsal root ganglion neurons

CCL2 [chemokine (C–C motif) ligand 2] contributes to the inflammation-induced neuropathic pain through activating VGSC (voltage-gated sodium channel)-mediated nerve impulse conduction, but the underlying mechanism is currently unknown. Our study aimed to investigate whether PKC (protein kinase C)–NF...

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Detalhes bibliográficos
Main Authors: Zhao, Rui, Pei, Guo-Xian, Cong, Rui, Zhang, Hang, Zang, Cheng-Wu, Tian, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2014
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062041/
https://ncbi.nlm.nih.gov/pubmed/24724624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140005
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