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Effect of PKC/NF-κB on the Regulation of P2X(3) Receptor in Dorsal Root Ganglion in Rats with Sciatic Nerve Injury

BACKGROUND: Protein kinase C (PKC), nuclear factor-kappa B p65 (NF-κB p65), and P2X(3) receptor (P2X(3)R) play significant roles in the sensitization and transduction of nociceptive signals, which are considered as potential targets for the treatment of neuropathic pain. However, the mechanisms and...

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Bibliographische Detailangaben
Veröffentlicht in:Pain Res Manag
Hauptverfasser: Li, Xue, Yuan, Jie, Yu, Xuan, Zhang, Qin, Qin, Bangyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519985/
https://ncbi.nlm.nih.gov/pubmed/33014214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7104392
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