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Effect of PKC/NF-κB on the Regulation of P2X(3) Receptor in Dorsal Root Ganglion in Rats with Sciatic Nerve Injury

BACKGROUND: Protein kinase C (PKC), nuclear factor-kappa B p65 (NF-κB p65), and P2X(3) receptor (P2X(3)R) play significant roles in the sensitization and transduction of nociceptive signals, which are considered as potential targets for the treatment of neuropathic pain. However, the mechanisms and...

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Detalhes bibliográficos
Publicado no:Pain Res Manag
Main Authors: Li, Xue, Yuan, Jie, Yu, Xuan, Zhang, Qin, Qin, Bangyong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519985/
https://ncbi.nlm.nih.gov/pubmed/33014214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7104392
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