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Effect of PKC/NF-κB on the Regulation of P2X(3) Receptor in Dorsal Root Ganglion in Rats with Sciatic Nerve Injury

BACKGROUND: Protein kinase C (PKC), nuclear factor-kappa B p65 (NF-κB p65), and P2X(3) receptor (P2X(3)R) play significant roles in the sensitization and transduction of nociceptive signals, which are considered as potential targets for the treatment of neuropathic pain. However, the mechanisms and...

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Publicat a:Pain Res Manag
Autors principals: Li, Xue, Yuan, Jie, Yu, Xuan, Zhang, Qin, Qin, Bangyong
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519985/
https://ncbi.nlm.nih.gov/pubmed/33014214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7104392
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