CC chemokine ligand 2 upregulates the current density and expression of TRPV1 channels and Na(v)1.8 sodium channels in dorsal root ganglion neurons

BACKGROUND: Inflammation or nerve injury-induced upregulation and release of chemokine CC chemokine ligand 2 (CCL2) within the dorsal root ganglion (DRG) is believed to enhance the activity of DRG nociceptive neurons and cause hyperalgesia. Transient receptor potential vanilloid receptor 1 (TRPV1) a...

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Main Authors: Kao, Der-Jang, Li, Allen H, Chen, Jin-Chung, Luo, Ro-Sun, Chen, Ying-Ling, Lu, Juu-Chin, Wang, Hung-Li
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458897/
https://ncbi.nlm.nih.gov/pubmed/22870919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-189
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