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Na(+) Channel Scn1b Gene Regulates Dorsal Root Ganglion Nociceptor Excitability in Vivo
Nociceptive dorsal root ganglion (DRG) neurons express tetrodotoxin-sensitive (TTX-S) and -resistant (TTX-R) Na(+) current (I(Na)) mediated by voltage-gated Na(+) channels (VGSCs). In nociceptive DRG neurons, VGSC β2 subunits, encoded by Scn2b, selectively regulate TTX-S α subunit mRNA and protein e...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123059/ https://ncbi.nlm.nih.gov/pubmed/21555511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.242370 |
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