DNA prime–protein boost increased the titer, avidity and persistence of anti-Aβ antibodies in wild-type mice

Recently, we reported that a DNA vaccine, composed of three copies of a self B cell epitope of amyloid-β (Aβ(42)) and the foreign T-cell epitope, Pan DR epitope (PADRE), generated strong anti-Aβ immune responses in wild-type and amyloid precursor protein transgenic animals. Although DNA vaccines hav...

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Detalhes bibliográficos
Main Authors: Davtyan, H, Mkrtichyan, M, Movsesyan, N, Petrushina, I, Mamikonyan, G, Cribbs, DH, Agadjanyan, MG, Ghochikyan, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820600/
https://ncbi.nlm.nih.gov/pubmed/19865176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.140
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