Endothelial permeability is controlled by spatially defined cytoskeletal mechanics: AFM force mapping of pulmonary endothelial monolayer

Actomyosin contraction directly regulates endothelial cell (EC) permeability, but intracellular redistribution of cytoskeletal tension associated with EC permeability is poorly understood. We used atomic force microscopy (AFM), EC permeability assays and fluorescence microscopy to link barrier regul...

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Bibliographic Details
Main Authors: Birukova, Anna A., Arce, Fernando T., Moldobaeva, Nurgul, Dudek, Steven M., Garcia, Joe G.N., Lal, Ratnesh, Birukov, Konstantin G.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820397/
https://ncbi.nlm.nih.gov/pubmed/18824415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.07.002
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