Endothelial permeability is controlled by spatially defined cytoskeletal mechanics: AFM force mapping of pulmonary endothelial monolayer

Actomyosin contraction directly regulates endothelial cell (EC) permeability, but intracellular redistribution of cytoskeletal tension associated with EC permeability is poorly understood. We used atomic force microscopy (AFM), EC permeability assays and fluorescence microscopy to link barrier regul...

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Hauptverfasser: Birukova, Anna A., Arce, Fernando T., Moldobaeva, Nurgul, Dudek, Steven M., Garcia, Joe G.N., Lal, Ratnesh, Birukov, Konstantin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820397/
https://ncbi.nlm.nih.gov/pubmed/18824415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.07.002
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