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Dual role of vinculin in barrier-disruptive and barrier-enhancing endothelial cell responses

Endothelial cell (EC) barrier disruption induced by edemagenic agonists such as thrombin is a result of increased actomyosin contraction and enforcement of focal adhesions (FA) anchoring contracting stress fibers, which leads to cell retraction and force-induced disruption of cell junctions. In turn...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Signal
Main Authors: Birukova, Anna A., Shah, Alok S., Tian, Yufeng, Moldobaeva, Nurgul, Birukov, Konstantin G.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831716/
https://ncbi.nlm.nih.gov/pubmed/26923917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.02.015
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