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IDH1 and IDH2 Mutations in Gliomas
BACKGROUND: A recent genomewide mutational analysis of glioblastomas (World Health Organization [WHO] grade IV glioma) revealed somatic mutations of the isocitrate dehydrogenase 1 gene (IDH1) in a fraction of such tumors, most frequently in tumors that were known to have evolved from lower-grade gli...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
2009
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820383/ https://ncbi.nlm.nih.gov/pubmed/19228619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0808710 |
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