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Activation of the CFTR Cl(−) channel by trimethoxyflavone in vitro and in vivo

The flavone apigenin has been previously selected as a potent pharmacological activator of the CFTR Cl(−) channel, however, its utility for the activation of CFTR in vivo is expected to be limited because flavonoids are readily metabolized. We therefore investigated the poorly metabolizable methylet...

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Hlavní autoři: Fischer, Horst, Illek, Beate
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820299/
https://ncbi.nlm.nih.gov/pubmed/19088450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000185552
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