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Oxidative Stress By Pyocyanin Impairs CFTR Cl(-) Transport In Human Bronchial Epithelial Cells
Pyocyanin (N-methyl-1-hydroxyphenazine), a redox-active virulence factor produced by the human pathogen Pseudomonas aeruginosa, is known to compromise mucociliary clearance. Exposure of human bronchial epithelial cells to pyocyanin increased the rate of cellular release of H(2)O(2) 3-fold above the...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2008
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628806/ https://ncbi.nlm.nih.gov/pubmed/18845244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.09.011 |
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