Oxidative Stress By Pyocyanin Impairs CFTR Cl(-) Transport In Human Bronchial Epithelial Cells

Pyocyanin (N-methyl-1-hydroxyphenazine), a redox-active virulence factor produced by the human pathogen Pseudomonas aeruginosa, is known to compromise mucociliary clearance. Exposure of human bronchial epithelial cells to pyocyanin increased the rate of cellular release of H(2)O(2) 3-fold above the...

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Main Authors: Schwarzer, Christian, Fischer, Horst, Kim, Eun-Jin, Barber, Katharine J., Mills, Aaron D., Kurth, Mark J., Gruenert, Dieter C., Suh, Jung H., Machen, Terry E., Illek, Beate
格式: Artigo
語言:Inglês
出版: 2008
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628806/
https://ncbi.nlm.nih.gov/pubmed/18845244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.09.011
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