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Activation of the CFTR Cl(−) channel by trimethoxyflavone in vitro and in vivo
The flavone apigenin has been previously selected as a potent pharmacological activator of the CFTR Cl(−) channel, however, its utility for the activation of CFTR in vivo is expected to be limited because flavonoids are readily metabolized. We therefore investigated the poorly metabolizable methylet...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820299/ https://ncbi.nlm.nih.gov/pubmed/19088450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000185552 |
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