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Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T

Airways secrete considerable amounts of acid. In this study, we investigated the identity and the pH-dependent function of the apical H(+) channel in the airway epithelium. In pH stat recordings of confluent JME airway epithelia in Ussing chambers, Zn-sensitive acid secretion was activated at a muco...

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Detalhes bibliográficos
Main Authors: Iovannisci, David, Illek, Beate, Fischer, Horst
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894549/
https://ncbi.nlm.nih.gov/pubmed/20548053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910379
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