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Sensitivity of Chloride Efflux vs. Transepithelial Measurements in Mixed CF and Normal Airway Epithelial Cell Populations

Background/Aims: While the Cl(-) efflux assays are relatively straightforward, their ability to assess the efficacy of phenotypic correction in cystic fibrosis (CF) tissue or cells may be limited. Accurate assessment of therapeutic efficacy, i.e., correlating wild type CF transmembrane conductance r...

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Detalhes bibliográficos
Main Authors: Illek, Beate, Lei, Dachuan, Fischer, Horst, Gruenert, Dieter C.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221260/
https://ncbi.nlm.nih.gov/pubmed/21220929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000324011
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