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Innate immunity against bacterial infection following hyperoxia exposure is impaired in Nrf2-deficient mice

Oxygen supplementation is used as therapy to support critically ill patients with severe respiratory impairment. Although hyperoxia has been shown to enhance the lung susceptibility to subsequent bacterial infection, the mechanisms underlying enhanced susceptibility remain enigmatic. We have reporte...

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Autores principales: Reddy, Narsa M., Suryanarayana, Vegiraju, Kalvakolanu, Dhananjaya V, Yamamoto, Masayuki, Kensler, Thomas W., Hassoun, Paul M., Kleeberger, Steven R., Reddy, Sekhar P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820249/
https://ncbi.nlm.nih.gov/pubmed/19734219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901754
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