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Innate immunity against bacterial infection following hyperoxia exposure is impaired in Nrf2-deficient mice

Oxygen supplementation is used as therapy to support critically ill patients with severe respiratory impairment. Although hyperoxia has been shown to enhance the lung susceptibility to subsequent bacterial infection, the mechanisms underlying enhanced susceptibility remain enigmatic. We have reporte...

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Bibliografiske detaljer
Main Authors: Reddy, Narsa M., Suryanarayana, Vegiraju, Kalvakolanu, Dhananjaya V, Yamamoto, Masayuki, Kensler, Thomas W., Hassoun, Paul M., Kleeberger, Steven R., Reddy, Sekhar P.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820249/
https://ncbi.nlm.nih.gov/pubmed/19734219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901754
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