The Hunt for 8-Oxoguanine Deaminase

[Image: see text] An enzyme from Pseudomonas aeruginosa, Pa0142 (gi|9945972) has been identified for the first time that is able to catalyze the deamination of 8-oxoguanine (8-oxoG) to uric acid. 8-Oxoguanine is formed by the oxidation of guanine residues within DNA by reactive oxygen species and th...

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Bibliografiske detaljer
Main Authors: Hall, Richard S., Fedorov, Alexander A., Marti-Arbona, Ricardo, Fedorov, Elena V., Kolb, Peter, Sauder, J. Michael, Burley, Stephen K., Shoichet, Brian K., Almo, Steven C., Raushel, Frank M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820149/
https://ncbi.nlm.nih.gov/pubmed/20088583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909817d
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