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YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis1-3. The pivotal effector of this pathway is YAP, a transcriptional co-activator amplified in mouse and human cancers, where it promotes epithelial to mesenc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Jianmin, Ji, Jun-Yuan, Yu, Min, Overholtzer, Michael, Smolen, Gromoslaw A., Wang, Rebecca, Brugge, Joan S., Dyson, Nicholas J., Haber, Daniel A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819909/
https://ncbi.nlm.nih.gov/pubmed/19935651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1993
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