YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis1-3. The pivotal effector of this pathway is YAP, a transcriptional co-activator amplified in mouse and human cancers, where it promotes epithelial to mesenc...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhang, Jianmin, Ji, Jun-Yuan, Yu, Min, Overholtzer, Michael, Smolen, Gromoslaw A., Wang, Rebecca, Brugge, Joan S., Dyson, Nicholas J., Haber, Daniel A.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819909/
https://ncbi.nlm.nih.gov/pubmed/19935651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1993
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items