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YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis1-3. The pivotal effector of this pathway is YAP, a transcriptional co-activator amplified in mouse and human cancers, where it promotes epithelial to mesenc...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819909/ https://ncbi.nlm.nih.gov/pubmed/19935651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1993 |
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