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YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis1-3. The pivotal effector of this pathway is YAP, a transcriptional co-activator amplified in mouse and human cancers, where it promotes epithelial to mesenc...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819909/ https://ncbi.nlm.nih.gov/pubmed/19935651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1993 |
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