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Nanoparticulate Quillaja saponin induces apoptosis in human leukemia cell lines with a high therapeutic index

Saponin fractions of Quillaja saponaria Molina (QS) have cytotoxic activity against cancer cells in vitro, but are too toxic to be useful in the clinic. The toxic effect was abolished by converting QS fractions into stable nanoparticles through the binding of QS to cholesterol. Two fractions of QS w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hu, Kefei, Berenjian, Saideh, Larsson, Rolf, Gullbo, Joachim, Nygren, Peter, Lövgren, Tanja, Morein, Bror
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819906/
https://ncbi.nlm.nih.gov/pubmed/20161987
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