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Aminopeptidase N (CD13) as a target for cancer chemotherapy

The enzyme aminopeptidase N (APN, also known as CD13) is a Zn(2+) dependent membrane‐bound ectopeptidase that degrades preferentially proteins and peptides with a N‐terminal neutral amino acid. Aminopeptidase N has been associated with the growth of different human cancers and suggested as a suitabl...

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Publicado en:Cancer Sci
Main Authors: Wickström, Malin, Larsson, Rolf, Nygren, Peter, Gullbo, Joachim
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188354/
https://ncbi.nlm.nih.gov/pubmed/21205077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2010.01826.x
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