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Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
In cancer cells, genetic alterations can activate proto-oncogenes, thereby contributing to tumorigenesis. However, the protein products of oncogenes are sometimes over-expressed without alteration of the proto-oncogene. Helping to explain this phenomenon, we found that when compared to similarly pro...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819821/ https://ncbi.nlm.nih.gov/pubmed/19703394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.06.016 |
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