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Aberrant Ki‐67 expression through 3′UTR alternative polyadenylation in breast cancers
Ki‐67 (MKI67) is a marker of cellular proliferation of cancer. Here, we show that Ki‐67 is post‐transcriptionally regulated through alternative polyadenylation (APA) and microRNAs in breast cancer. We show that shortening of the Ki‐67 3′UTR results in the loss of the binding sites for the suppressiv...
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| Publicado no: | FEBS Open Bio |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832968/ https://ncbi.nlm.nih.gov/pubmed/29511610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12364 |
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