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Aberrant Alternative Polyadenylation is Responsible for Survivin Up-regulation in Ovarian Cancer

BACKGROUND: Survivin is an oncoprotein silenced in normal mature tissues but reactivated in serous ovarian cancer (SOC). Although transcriptional activation is assumed for its overexpression, the long 3'-untranslated region (3'-UTR) in survivin gene, which contains many alternate polyadeny...

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Detalhes bibliográficos
Publicado no:Chin Med J (Engl)
Main Authors: He, Xiang-Jun, Zhang, Qi, Ma, Li-Ping, Li, Na, Chang, Xiao-Hong, Zhang, Yu-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878157/
https://ncbi.nlm.nih.gov/pubmed/27174320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0366-6999.181965
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