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Elevated Levels of Insulin-Like Growth Factor (IGF)-I in Serum Rescue the Severe Growth Retardation of IGF-I Null Mice

IGF-I plays a vital role in growth and development and acts in an endocrine and an autocrine/paracrine fashion. The purpose of the current study was to clarify whether elevated levels of IGF-I in serum can rescue the severe growth retardation and organ development and function of igf-I null mice. To...

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Autori principali: Wu, YingJie, Sun, Hui, Yakar, Shoshana, LeRoith, Derek
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819739/
https://ncbi.nlm.nih.gov/pubmed/19497975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0272
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