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Assembly of the Sos1-Grb2-Gab1 Ternary Signaling Complex Is Under Allosteric Control

Allostery has evolved as a form of local communication between interacting protein partners allowing them to quickly sense changes in their immediate vicinity in response to external cues. Herein, using isothermal titration calorimetry (ITC) in conjunction with circular dichroism (CD) and macromolec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McDonald, Caleb B., Seldeen, Kenneth L., Deegan, Brian J., Bhat, Vikas, Farooq, Amjad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819574/
https://ncbi.nlm.nih.gov/pubmed/20005866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.12.011
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