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Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc(1) complex

Ascochlorin is an isoprenoid antibiotic that is produced by the phytopathogenic fungus Ascochyta viciae. Similar to ascofuranone, which specifically inhibits trypanosome alternative oxidase by acting at the ubiquinol binding domain, ascochlorin is also structurally related to ubiquinol. When added t...

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Detalles Bibliográficos
Main Authors: Berry, Edward A., Huang, Li-shar, Lee, Dong-Woo, Daldal, Fevzi, Nagai, Kazuo, Minagawa, Nobuko
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819552/
https://ncbi.nlm.nih.gov/pubmed/20025846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2009.12.003
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