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Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc(1) complex

Ascochlorin is an isoprenoid antibiotic that is produced by the phytopathogenic fungus Ascochyta viciae. Similar to ascofuranone, which specifically inhibits trypanosome alternative oxidase by acting at the ubiquinol binding domain, ascochlorin is also structurally related to ubiquinol. When added t...

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Détails bibliographiques
Auteurs principaux: Berry, Edward A., Huang, Li-shar, Lee, Dong-Woo, Daldal, Fevzi, Nagai, Kazuo, Minagawa, Nobuko
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819552/
https://ncbi.nlm.nih.gov/pubmed/20025846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2009.12.003
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