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Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc(1) complex

Ascochlorin is an isoprenoid antibiotic that is produced by the phytopathogenic fungus Ascochyta viciae. Similar to ascofuranone, which specifically inhibits trypanosome alternative oxidase by acting at the ubiquinol binding domain, ascochlorin is also structurally related to ubiquinol. When added t...

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Bibliografiske detaljer
Main Authors: Berry, Edward A., Huang, Li-shar, Lee, Dong-Woo, Daldal, Fevzi, Nagai, Kazuo, Minagawa, Nobuko
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819552/
https://ncbi.nlm.nih.gov/pubmed/20025846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2009.12.003
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