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Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc(1) complex
Ascochlorin is an isoprenoid antibiotic that is produced by the phytopathogenic fungus Ascochyta viciae. Similar to ascofuranone, which specifically inhibits trypanosome alternative oxidase by acting at the ubiquinol binding domain, ascochlorin is also structurally related to ubiquinol. When added t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819552/ https://ncbi.nlm.nih.gov/pubmed/20025846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2009.12.003 |
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