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Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis
Activation of complement occurs during autoimmune retinal and intraocular inflammatory disease as well as neuroretinal degenerative disorders. The cleavage of C5 into fragments C5a and C5b is a critical event during the complement cascade. C5a is a potent proinflammatory anaphylatoxin capable of ind...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819496/ https://ncbi.nlm.nih.gov/pubmed/20002447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.04070.x |
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