Monoclonal Antibody-Mediated CD200 Receptor Signaling Suppresses Macrophage Activation and Tissue Damage in Experimental Autoimmune Uveoretinitis

Macrophage responses are regulated by multiple secreted factors as well as by cell surface receptors, including the inhibitory signals resulting from ligation of myeloid CD200 receptors (CD200R) by the widely distributed CD200. In the absence of CD200, animals display increased susceptibility to aut...

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Autori principali: Copland, David A., Calder, Claudia J., Raveney, Ben J.E., Nicholson, Lindsay B., Phillips, Joseph, Cherwinski, Holly, Jenmalm, Maria, Sedgwick, Jonathon D., Dick, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2007
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934542/
https://ncbi.nlm.nih.gov/pubmed/17600119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070272
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