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Tissue-Resident Exhausted Effector Memory CD8(+) T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis

Experimental autoimmune uveoretinitis is a model for noninfectious posterior segment intraocular inflammation in humans. Although this disease is CD4(+) T cell dependent, in the persistent phase of disease CD8(+) T cells accumulate. We show that these are effector memory CD8(+) T cells that differ f...

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Bibliografiske detaljer
Main Authors: Boldison, Joanne, Chu, Colin J., Copland, David A., Lait, Philippa J. P., Khera, Tarnjit K., Dick, Andrew D., Nicholson, Lindsay B.
Format: Artigo
Sprog:Inglês
Udgivet: AAI 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009498/
https://ncbi.nlm.nih.gov/pubmed/24740509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301390
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