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Tissue-Resident Exhausted Effector Memory CD8(+) T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis
Experimental autoimmune uveoretinitis is a model for noninfectious posterior segment intraocular inflammation in humans. Although this disease is CD4(+) T cell dependent, in the persistent phase of disease CD8(+) T cells accumulate. We show that these are effector memory CD8(+) T cells that differ f...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
AAI
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4009498/ https://ncbi.nlm.nih.gov/pubmed/24740509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301390 |
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