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Constitutive Retinal CD200 Expression Regulates Resident Microglia and Activation State of Inflammatory Cells during Experimental Autoimmune Uveoretinitis

Recent evidence supports the notion that tissue OX2 (CD200) constitutively provides down-regulatory signals to myeloid-lineage cells via CD200-receptor (CD200R). Thus, mice lacking CD200 (CD200(−/−)) show increased susceptibility to and accelerated onset of tissue-specific autoimmunity. In the retin...

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Detalhes bibliográficos
Main Authors: Broderick, Cathryn, Hoek, Robert M., Forrester, John V., Liversidge, Janet, Sedgwick, Jonathon D., Dick, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850781/
https://ncbi.nlm.nih.gov/pubmed/12414514
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