Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome

We hypothesized that sirolimus, an mTOR inhibitor, may be effective in patients with autoimmune lymphoproliferative syndrome (ALPS) and treated patients who were intolerant to or failed other therapies. Four patients were treated for autoimmune cytopenias; all had a rapid complete or near complete r...

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Bibliografische gegevens
Hoofdauteurs: Teachey, David T., Greiner, Robert, Seif, Alix, Attiyeh, Edward, Bleesing, Jack, Choi, John, Manno, Catherine, Rappaport, Eric, Schwabe, Dirk, Sheen, Cecilia, Sullivan, Kathleen E., Zhuang, Hongming, Wechsler, Daniel S., Grupp, Stephan A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819393/
https://ncbi.nlm.nih.gov/pubmed/19208097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2009.07595.x
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