Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6(−/−) mice

Elucidation of the metabolic pathways of triacylglycerol (TAG) synthesis is critical to the understanding of chronic metabolic disorders such as obesity, cardiovascular disease, and diabetes. sn-Glycerol-3-phosphate acyltransferase (GPAT) and sn-1-acylglycerol-3-phosphate acyltransferase (AGPAT) cat...

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Hauptverfasser: Nagle, Cynthia A., Vergnes, Laurent, DeJong, Hendrik, Wang, Shuli, Lewin, Tal M., Reue, Karen, Coleman, Rosalind A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819352/
https://ncbi.nlm.nih.gov/pubmed/18192653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M700592-JLR200
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