Hepatic Overexpression of Glycerol-sn-3-phosphate Acyltransferase 1 in Rats Causes Insulin Resistance

Fatty liver is commonly associated with insulin resistance and type 2 diabetes, but it is unclear whether triacylglycerol accumulation or an excess flux of lipid intermediates in the pathway of triacyglycerol synthesis are sufficient to cause insulin resistance in the absence of genetic or diet-indu...

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Hlavní autoři: Nagle, Cynthia A., An, Jie, Shiota, Masakazu, Torres, Tracy P., Cline, Gary W., Liu, Zhen-Xiang, Wang, Shuli, Catlin, ReEtta L., Shulman, Gerald I., Newgard, Christopher B., Coleman, Rosalind A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819346/
https://ncbi.nlm.nih.gov/pubmed/17389595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611550200
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