SMAD4 Gene Mutations Are Associated With Poor Prognosis in Pancreatic Cancer

PURPOSE: Recently, the majority of protein coding genes were sequenced in a collection of pancreatic cancers, providing an unprecedented opportunity to identify genetic markers of prognosis for patients with adenocarcinoma of the pancreas. EXPERIMENTAL DESIGN: We previously sequenced over 750 millio...

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Detalhes bibliográficos
Main Authors: Blackford, Amanda, Serrano, Oscar K., Wolfgang, Christopher, Parmigiani, Giovanni, Jones, Siân, Zhang, Xiaosong, Parsons, D. Williams, Lin, Jimmy Cheng-Ho, Leary, Rebecca J., Eshleman, James R., Goggins, Michael, Jaffee, Elizabeth M., Iacobuzio-Donahue, Christine A., Maitra, Anirban, Cameron, John L., Olino, Kelly, Schulick, Richard, Winter, Jordan, Herman, Joseph M., Laheru, Daniel, Vogelstein, Bert, Kinzler, Kenneth W., Velculescu, Victor E., Hruban, Ralph H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819274/
https://ncbi.nlm.nih.gov/pubmed/19584151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0227
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