Genetic Mutations Associated With Cigarette Smoking in Pancreatic Cancer

BACKGROUND: Cigarette smoking doubles the risk of pancreatic cancer and smoking accounts for 20 to 25% of pancreatic cancers. The recent sequencing of the pancreatic cancer genome provides an unprecedented opportunity to identify mutational patterns associated with smoking. DESIGN: We previously seq...

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Main Authors: Blackford, Amanda, Parmigiani, Giovanni, Kensler, Thomas W., Wolfgang, Christopher, Jones, Siân, Zhang, Xiaosong, Parsons, D. Willams, Lin, Jimmy Cheng-Ho, Leary, Rebecca J., Eshleman, James R., Goggins, Michael, Jaffee, Elizabeth M., Iacobuzio-Donahue, Christine A., Maitra, Anirban, Klein, Alison, Cameron, John L., Olino, Kelly, Schulick, Richard, Winter, Jordan, Vogelstein, Bert, Velculescu, Victor E., Kinzler, Kenneth W., Hruban, Ralph H.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669837/
https://ncbi.nlm.nih.gov/pubmed/19351817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0015
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