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CXC Motif: A Functional Mimic of Protein Disulfide Isomerase
Protein disulfide isomerase (PDI) utilizes the active-site sequence Cys–Gly–His–Cys (CGHC; E°′ = −180 mV) to effect thiol–disulfide interchange during oxidative protein folding. Here, the Cys–Gly–Cys-NH(2) (CGC) peptide is shown to have a disulfide reduction potential (E°′ = −167 mV) that is close t...
Bewaard in:
| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2003
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819094/ https://ncbi.nlm.nih.gov/pubmed/12731880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi026993q |
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