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Functional Differences in Yeast Protein Disulfide Isomerases

PDI1 is the essential gene encoding protein disulfide isomerase in yeast. The Saccharomyces cerevisiae genome, however, contains four other nonessential genes with homology to PDI1: MPD1, MPD2, EUG1, and EPS1. We have investigated the effects of simultaneous deletions of these genes. In several case...

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Autori principali: Nørgaard, Per, Westphal, Vibeke, Tachibana, Christine, Alsøe, Lene, Holst, Bjørn, Winther, Jakob R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195995/
https://ncbi.nlm.nih.gov/pubmed/11157982
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