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CXC Motif: A Functional Mimic of Protein Disulfide Isomerase

Protein disulfide isomerase (PDI) utilizes the active-site sequence Cys–Gly–His–Cys (CGHC; E°′ = −180 mV) to effect thiol–disulfide interchange during oxidative protein folding. Here, the Cys–Gly–Cys-NH(2) (CGC) peptide is shown to have a disulfide reduction potential (E°′ = −167 mV) that is close t...

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Main Authors: Woycechowsky, Kenneth J., Raines, Ronald T.
格式: Artigo
語言:Inglês
出版: 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819094/
https://ncbi.nlm.nih.gov/pubmed/12731880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi026993q
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