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Context-dependent regulatory mechanism of the splicing factor hnRNP L

Splicing regulatory proteins often have distinct activities when bound to exons versus introns. However, less clear is whether variables besides location can influence activity. HnRNP L binds to a motif present in both CD45 variable exons 4 and 5 to affect their coordinate repression. Here we show t...

詳細記述

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書誌詳細
主要な著者: Motta-Mena, Laura B., Heyd, Florian, Lynch, Kristen W.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818868/
https://ncbi.nlm.nih.gov/pubmed/20122404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.12.027
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