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Context-dependent regulatory mechanism of the splicing factor hnRNP L
Splicing regulatory proteins often have distinct activities when bound to exons versus introns. However, less clear is whether variables besides location can influence activity. HnRNP L binds to a motif present in both CD45 variable exons 4 and 5 to affect their coordinate repression. Here we show t...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818868/ https://ncbi.nlm.nih.gov/pubmed/20122404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.12.027 |
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