Llwytho...

Synthetic studies and pharmacological evaluations on the MDMA (“Ecstasy”) antagonist Nantenine

The naturally occurring aporphine alkaloid nantenine, has been shown to antagonize behavioral and physiological effects of MDMA in mice. We have synthesized (±)-nantenine via an oxidative cyclization reaction with PIFA and evaluated its binding profile against a panel of CNS targets. To begin to und...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: LeGendre, Onica, Pecic, Stevan, Chaudhary, Sandeep, Zimmerman, Sarah M., Fantegrossi, William E., Harding, Wayne W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818532/
https://ncbi.nlm.nih.gov/pubmed/19963380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.11.053
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