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Microwave-Assisted Direct Biaryl Coupling: First Application to the Synthesis of Aporphines

We have investigated the use of microwaves in a direct biaryl coupling reaction for the synthesis of analogs of the aporphine alkaloid nantenine. Our study shows that the aporphine core may be rapidly accessed from benzyl-tetrahydroisoquinoline substrates with this method. This is the first report o...

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Bibliographic Details
Main Authors: Chaudhary, Sandeep, Pecic, Stevan, LeGendre, Onica, Harding, Wayne W.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704556/
https://ncbi.nlm.nih.gov/pubmed/20161231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.03.029
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