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Airway proteins involved in bacterial clearance susceptible to cathepsin G proteolysis
INTRODUCTION: Serine proteases released from neutrophils are central to the pathogenesis of cystic fibrosis lung disease and considered obvious therapeutic targets. Neutrophil elastase digests key opsonins present in the lung and disrupts phagocytosis, allowing bacteria to persist despite establishe...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818476/ https://ncbi.nlm.nih.gov/pubmed/19679607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00020809 |
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