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Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages
Cathepsin E is an endosomal aspartic proteinase that is predominantly expressed in immune-related cells. Recently, we showed that macrophages derived from cathepsin E-deficient (CatE (−/−)) mice display accumulation of lysosomal membrane proteins and abnormal membrane trafficking. In this study, we...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855462/ https://ncbi.nlm.nih.gov/pubmed/24340026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082415 |
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